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ea0081p182 | Reproductive and Developmental Endocrinology | ECE2022

Defining reference ranges for serum anti-Müllerian hormone (AMH) on a large cohort of normozoospermic adult men highlights new potential physiological functions of AMH on FSH secretion and sperm motility

Benderradji Hamza , Anne-Laure Barbotin , Maryse Leroy-Billiard , Julie Prasivoravong , Francois Marcelli , Christine Decanter , Geoffroy Robin , Valerie Mitchell , Jean-Marc Rigot , Antonino Bongiovanni , Florent Sauve , Luc Buee , Claude-Alain Maurage , Maryse Cartigny , Arnauld Villers , Vincent Prevot , Sophie Catteau-Jonard , Nicolas Sergeant , Paolo Giacobini , Pascal Pigny , Clara Leroy

Background: Few studies to date have attempted to measure serum anti-Müllerian hormone (AMH) levels in adult men, and solid references ranges have not yet been defined on a large cohort.Objective: In this study, we aimed to first establish the reference ranges for serum AMH and AMH-to-total testosterone ratio (AMH/tT) in adult males. Secondly, we investigated the relationship between serum AMH and both reproductive hormones and semen parameters....

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ea0063oc7.5 | Endocrine Connections 1 | ECE2019

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) syndrome: French prospective study in a cohort of 25 patients

Humbert Linda , Dubucquoi Sylvain , Kemp Helen , Veber Pascale Saugier , Fabien Nicole , Top Isabelle Raymond , Bauters Catherine Cardot , Cartigny Maryse , Delemer Brigitte , Docao Christine , Penfornis Alfred , Guignat Laurence , Kerlan Veronique , Lefevbre Herve , Chabre Olivier , Vanhove Laura , Sendid Boualem , Carel Jean-Claude , Souchon Perre-Francois , Weil Jacques , Vantyghem Marie-Christine , Wemeau Jean-Louis , Proust-Lemoine Emmanuelle

Background: APECED syndrome is a rare monogenic disease caused by homozygous mutation of AIRE gene. It classically presents with chronic mucocutaneous candidiasis (CMC), hypoparathyroidism (HP), and adrenal insufficiency (AI) with an early onset in childhood. Non-endocrine manifestations as ectodermic dystrophy, asplenism and pneumonitis are also observed but their incidence remains unknown and their mechanisms not well understood. APECED has been poorly reported in France alt...

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Endocrine Abstracts

Defining reference ranges for serum anti-Müllerian hormone (AMH) on a large cohort of normozoospermic adult men highlights new potential physiological functions of AMH on FSH secretion and sperm motility

Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy (APECED) syndrome: French prospective study in a cohort of 25 patients

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